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Medical Science Monitor Basic Research


A Rare Case of a Ruptured Metastatic Hepatic Lesion from a Jejunal Gastrointestinal Stromal Tumor (GIST) Treated by Arterial Embolization

Challenging differential diagnosis, Rare disease

Hassan Salame, Mahdi Issa, Gregory Nicolas, Juliano Haddad, Marwan M. Haddad, Firas S. Farhat, Hussein Moubarak, Tony Kfoury, Elie Zaghrini, Raja Wakim

Lebanon Department of General Surgery, Al Zahraa Hospital, Beirut, Lebanon

Am J Case Rep 2018; 19:1480-1487

DOI: 10.12659/AJCR.910061

Available online:

Published: 2018-12-13


BACKGROUND: Gastrointestinal stromal tumors (GISTs) are rare gastrointestinal neoplasms. The spontaneous rupture of a jejunal GIST is very rare and spontaneous rupture of liver metastasis from an intestinal GIST is even rarer with only a few cases reported in the literature.
CASE REPORT: In this article, we reported a case of spontaneous rupture of a liver metastasis from a malignant jejunal GIST that presented with active tumoral bleeding, hypovolemic shock, and hemoperitoneum. The patient was successfully treated with arterial embolization of the tumor.
CONCLUSIONS: In appropriately selected patients, arterial embolization appears to be an effective safe treatment for a GIST metastasis rupture.

Keywords: Chemoembolization, Therapeutic, Endoscopy, Gastrointestinal, Gastrointestinal Hemorrhage