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Sonographic Features of Flat Epithelial Atypia Manifesting as a Non-Mass-Like Lesion: A Case Report

Rare disease

Suk Jung Kim, Woo Gyeong Kim

Department of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea

Am J Case Rep 2019; 20:340-344

DOI: 10.12659/AJCR.914178

Available online:

Published: 2019-03-15

BACKGROUND: The incidence of flat epithelial atypia of the breast has been increasing owing to the increasing use of ultrasonography (US) and US-guided core needle biopsy. However, reports describing the sonographic features of flat epithelial atypia are fewer than those on its mammographic features.
CASE REPORT: A 47-year-old female had a regular 6 month-interval follow-up US for multiple bilateral breast masses detected on US. A new focal non-mass-like lesion measuring 2 cm in maximum diameter was noted in the 10 o’clock direction of the right breast on the follow-up US. Mammography was not performed during the follow-up period. The patient had no breast symptoms and no family history of breast cancer or other pertinent medical history. US-guided 14-gauge core needle biopsy yielded a pathological diagnosis of flat epithelial atypia without upgrade to malignancy, and this was further confirmed after complete excision of the non-mass-like lesion.
CONCLUSIONS: Flat epithelial atypia can present as a focal non-mass-like lesion on US, which has not been reported previously.

Keywords: Breast, Breast Diseases, Ultrasonography, Mammary