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Iatrogenic Ventriculitis Due to Mycoplasma Hominis: A Case Report and Review of the Literature

Diagnostic / therapeutic accidents, Rare disease

Asim Diab, Safiya Sayed Mahmood AlMusawi, Dhoha Hudhaiah, Rania Magzoub, Abdullatif S. Al Rashed, Tariq S. Al Musawi

Department of Microbiology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia

Am J Case Rep 2019; 20:406-411

DOI: 10.12659/AJCR.914284

Available online:

Published: 2019-03-29

BACKGROUND: Mycoplasma hominis, which rarely causes infection after neurosurgical procedures, is a small free-living organism, belonging to the genus Mycoplasma. M. hominis lacks a rigid cell wall and cannot be clearly visualized by routine light microscopy. Thus, it is challenging to diagnose infections caused by this pathogen. Here, we report a case of Mycoplasma hominis causing iatrogenic ventriculitis secondary to extraventricular drain.
CASE REPORT: A 25-year-old man who was a victim of a road traffic accident developed M. hominis ventriculitis secondary to extraventricular drain. Despite a delay in the diagnosis due to the difficulty of identifying M. hominis, the patient was successfully treated with intravenous ciprofloxacin 400 mg for 14 days.
CONCLUSIONS: The findings of this case report, coupled with a thorough review of the literature, demonstrate the pathogenic potential of M. hominis. Particularly in developing countries, in which laboratories may have limited access to advanced technologies, such rare infectious diseases remain major diagnostic challenges.

Keywords: Central Nervous System Diseases, Cerebral Ventriculitis, Cross Infection, Meningitis, Mycoplasma hominis