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Early Stage Anaplastic Sarcomatoid Carcinoma of The Pancreas, A Case Report

Rare disease

Nedal Bukhari, Amani Joudeh

Department of Medical Oncology, King Fahad Specialist Hospital, Dammam, Saudi Arabia

Am J Case Rep 2019; 20:597-601

DOI: 10.12659/AJCR.915334

Available online:

Published: 2019-04-26

BACKGROUND: Anaplastic sarcomatoid carcinoma of the pancreas (ASCP) is a rare variant of pancreatic malignancies. It is a high-grade epithelial carcinoma predominated with spindle cells.
CASE REPORT: We report a case of a 65-year-old patient who presented with early stage, ampullary mass indicating malignancy, and who subsequently underwent pancreatoduodenectomy. Histopathology and immunohistochemistry were confirmatory for anaplastic, grade IV sarcomatoid adenocarcinoma arising from the head of the pancreas.
CONCLUSIONS: To our knowledge, this is a rare presentation with few cases reported in the literature.

Keywords: Adenocarcinoma, Ampulla of Vater, Carcinoma, Immunohistochemistry