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Simultaneous Surgery for Inferior Vena Cava Leiomyosarcoma with Multiple Hepatic Metastases: A Justified Challenge

Unusual or unexpected effect of treatment, Rare disease

Hiroyuko Motodaka, Bibek Aryal, Yoshiyuki Mizuta, Nobuhiro Tada, Kota Yoshikawa, Mamoru Kaieda, Yoshikazu Kawazu, Tamahiro Kinjo, Teruo Komokata

Department of Surgery, Kagoshima Medical Center, National Hospital Organization, Kagoshima City, Kagoshima, Japan

Am J Case Rep 2019; 20:902-907

DOI: 10.12659/AJCR.915995

Available online:

Published: 2019-06-25

BACKGROUND: Leiomyosarcoma of inferior vena cava (IVC), a rarely encountered malignancy originating from the smooth muscle cells of media of the IVC, frequently metastasize to the liver. The suggested treatment of choice of IVC leiomyosarcoma is radical en-bloc excision aimed to obtain a negative resection margin. There are a few reported cases of surgical management in patients with liver metastasis from IVC leiomyosarcoma.
CASE REPORT: This report describes a simultaneous surgical approach for a case of IVC leiomyosarcoma with multiple liver metastases followed by chemotherapy.
CONCLUSIONS: Tumor volume reduction surgery of metastatic lesions combined with radical resection of the primary tumor may provide better survival benefit in patients with advanced IVC leiomyosarcoma.

Keywords: Leiomyosarcoma, Neoplasm Metastasis, Vena Cava, Inferior