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25 June 2019 : Case report  Japan

Simultaneous Surgery for Inferior Vena Cava Leiomyosarcoma with Multiple Hepatic Metastases: A Justified Challenge

Unusual or unexpected effect of treatment, Rare disease

Hiroyuko Motodaka1ABEF, Bibek Aryal12ABEF, Yoshiyuki Mizuta1BEF, Nobuhiro Tada1BF, Kota Yoshikawa1AB, Mamoru Kaieda1AB, Yoshikazu Kawazu3AB, Tamahiro Kinjo3AB, Teruo Komokata1ABEF*

DOI: 10.12659/AJCR.915995

Am J Case Rep 2019; 20:902-907

Abstract

BACKGROUND: Leiomyosarcoma of inferior vena cava (IVC), a rarely encountered malignancy originating from the smooth muscle cells of media of the IVC, frequently metastasize to the liver. The suggested treatment of choice of IVC leiomyosarcoma is radical en-bloc excision aimed to obtain a negative resection margin. There are a few reported cases of surgical management in patients with liver metastasis from IVC leiomyosarcoma.

CASE REPORT: This report describes a simultaneous surgical approach for a case of IVC leiomyosarcoma with multiple liver metastases followed by chemotherapy.

CONCLUSIONS: Tumor volume reduction surgery of metastatic lesions combined with radical resection of the primary tumor may provide better survival benefit in patients with advanced IVC leiomyosarcoma.

Keywords: Leiomyosarcoma, Neoplasm Metastasis, Vena Cava, Inferior

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923