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Medical Science Monitor Basic Research


Post-Epstein-Barr Virus Acute Cerebellitis in an Adult

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction , Educational Purpose (only if useful for a systematic review or synthesis)

Shaikha Daoud Al-Shokri, Sameer Ahammed Karumannil, Saeed Saleh Mohammed, Mohamed Sulaiman Sadek

Qatar Department of Internal Medicine, Hamad General Hospital, Doha, Qatar

Am J Case Rep 2020; 21:e918567

DOI: 10.12659/AJCR.918567

Available online: 2020-01-06

Published: 2020-01-06


BACKGROUND: Acute cerebellitis in adults is a rare disease. The etiology is unknown but postulated to be due to primary infection or para-infection. Different presentations have been reported, which complicates the diagnosis process.
CASE REPORT: We report the case of a young man who presented with headache, vomiting, and vertigo. He was found to have ataxia and cerebellar signs, bradycardia magnetic resonance imaging (MRI) of the brain showed acute cerebellitis, and cerebrospinal fluid (CSF) studies showed lymphocytosis. Further investigations showed the presence of Epstein-Barr virus (EBV) immunoglobulin M (IgM) and IgG. His symptoms resolved completely with corticosteroid and antiviral treatments.
CONCLUSIONS: Acute cerebellitis can present in various ways. Bradycardia, along with neurological deficits, should raise the suspicion of acute cerebellitis.

Keywords: Cerebellar Diseases, Diffusion Magnetic Resonance Imaging, Epstein-Barr Virus Infections