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Concurrent Adrenal and Extra-Adrenal Ganglioneuromas: A Case Report

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Educational Purpose (only if useful for a systematic review or synthesis)

Maram Hussein AlGhamdi, Abdullah AlAyed, Nayef A. AlShabyli, Nour Hussain AlGhamdi, Mohannad AlRasheed

Saudi Arabia Department of Radiology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia

Am J Case Rep 2019; 20:1817-1820

DOI: 10.12659/AJCR.918568

Available online:

Published: 2019-12-06


#918568

BACKGROUND: Ganglioneuroma is a rare benign sympathetic chain neoplasm which rarely arise from the adrenal gland in adults and exceedingly rare for ganglioneuroma to arise from different origins in the same patient. We present a rare case of retroperitoneal ganglioneuroma concurring with an adrenal ganglioneuroma in an adult patient.
CASE REPORT: A 17-year-old healthy male underwent computed tomography (CT) scan after road traffic accident where he was found to have a left adrenal homogeneous hypovascular lesion with another retroperitoneal lesion seen within the right para-colic gutter with similar radiological features. Successful surgical resection was obtained, and histological diagnosis of both lesions was benign ganglioneuroma.
CONCLUSIONS: Adrenal and extra-adrenal ganglioneuroma can, although rare, concur together. Key findings are the similar radiological appearance of the lesions with typical hypovascular progressive pattern of enhancement. Appropriate pre-surgical diagnosis can aid to proper management since ganglioneuroma needs wide surgical resection due to its high chance of recurrence.

Keywords: Adrenal Glands, Ganglioneuroblastoma, Ganglioneuroma



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