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Medical Science Monitor Basic Research


Large Thyroglossal Duct Cyst: A Case Report

Unusual clinical course, Challenging differential diagnosis

Sarah Mortaja, Haneen Sebeih, Nasser W. Alobida, Khalid Al-Qahtani

Saudi Arabia College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

Am J Case Rep 2020; 21:e919745

DOI: 10.12659/AJCR.919745

Available online: 2020-04-02

Published: 2020-05-02


BACKGROUND: Thyroglossal duct cysts are the most common congenital neck cysts. They typically present in childhood and early adulthood, and average a size of 2-4 cm, but can also present in later adult life.
CASE REPORT: We present a case of a 36-year-old female patient with a very large midline neck mass, reaching the mandible superiorly. Patient history and physical examination, as well as computed tomography scan of her neck, confirmed the diagnosis of large thyroglossal duct cyst. She underwent Sistrunk procedure for thyroglossal duct cyst excision, and the specimen was sent for histopathological evaluation, which confirmed the diagnosis.
CONCLUSIONS: Thyroglossal duct cyst should be considered as a differential diagnosis in older patients and in patients with a relatively large neck mass.

Keywords: Thyroglossal Cyst, Thyroid Diseases, Thyroid Gland