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Medical Science Monitor Basic Research


Takayasu Arteritis Associated with Latent Tuberculosis Infection: A 39-Year-Old Woman Is the First Case in Gabon

Challenging differential diagnosis, Management of emergency care, Patient complains / malpractice, Rare disease

Guignali Laurette Mangouka, Berthe Amélie Iroungou, Berthold Bivigou-Mboumba, Davy Ngabou, El Medhi Badidi Moulay, Abdelatif Darbi, Jean Raymond Nzenze

Gabon Department of Internal Medicine, HIAOBO (Omar Bongo Ondimba Army Training Hospital), Libreville, Gabon

Am J Case Rep 2020; 21:e920195

DOI: 10.12659/AJCR.920195

Available online: 2020-06-12

Published: 2020-08-02


BACKGROUND: Takayasu disease is a rare disease affecting large vessels, particularly the aorta and its main branches. The affected arteries become partially occluded. The disease is more frequent in women under 40 years of age, with a ratio of women to men of 8: 1.
CASE REPORT: We report the case of a 39-year-old woman who was admitted to the medical ward at the Military Hospital in Gabon. She presented with multiple aneurysms, arterial stenosis, and a positive tuberculin skin test and was diagnosed with Takayasu disease associated with latent tuberculosis infection. This rare case is the first to be reported in Gabon, with a delay in diagnosis of approximately 7 months.
CONCLUSIONS: This is the first case of Takayasu arteritis that has been described in Gabon and has generated medical interest beyond the country regarding the diagnostic, therapeutic, and prognostic approach.

Keywords: Aortic Aneurysm, Abdominal, latent tuberculosis, Takayasu arteritis