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Medical Science Monitor Basic Research


Emergency Surgery in High Volume Osteosarcoma of Left Proximal Humerus Due to Vascular Compromise: A Case Report

Unusual clinical course, Management of emergency care, Clinical situation which can not be reproduced for ethical reasons

Istan Irmasyah Irsan, Maulana Hasymi Hutabarat, Satria Pandu Persada Isma, Eviana Norahmawati, Irma P. Darinafitri, William Putera Sukmajaya, Marvin Anthony Putera, Muhammad Hilman Bimadi

Indonesia Department of Orthopedics and Traumatology, Saiful Anwar General Hospital-Universitas Brawijaya, Malang, Indonesia

Am J Case Rep 2020; 21:e922257

DOI: 10.12659/AJCR.922257

Available online: 2020-04-22

Published: 2020-05-22


BACKGROUND: Osteosarcoma is the most common type of malignant bone tumor arising from mesenchymal stem cell. When occurring on the proximal humerus, it is associated with poor outcomes; there are numerous neurovascular structures around proximal humerus. Unfortunately, the degree of vascular involvement in osteosarcoma is rarely evaluated and reported. Thus, we would like to highlight our case.
CASE REPORT: We reported a case of left proximal humerus osteosarcoma causing dead limb in a 14-year-old boy. The dead limb progressed in the span of 3 weeks. An emergency forequarter amputation (FQA) was conducted to prevent further complications such as septicemia and mortality. Two months after the surgery, the patient had improved quality of life. One year after, the patient had no local recurrence. However, there was a lung metastasis detected 9 months after the surgery. The patient died 13 months after the surgery.
CONCLUSIONS: Osteosarcoma of the proximal humerus can potentially compromise vascular structures. Early diagnosis and treatment are mandatory to prevent such complications.

Keywords: Amputation, Bone Neoplasms, Humerus, Ischemia