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Medical Science Monitor Basic Research


A 29-Year-Old Male Construction Worker from India Who Presented with Left- Sided Abdominal Pain Due to Isolated Superior Mesenteric Vein Thrombosis Associated with SARS-CoV-2 Infection

Rare co-existance of disease or pathology

Suresh Kumar Thuluva, Hongguang Zhu, Mark M. L. Tan, Saurav Gupta, Kuan Yuen Yeong, See Toh Cheong Wah, Li Lin, Eng Soo Yap

Singapore Department of Radiology, Ng Teng Fong General Hospital, National University Health System (NUHS), Singapore, Singapore

Am J Case Rep 2020; 21:e926785

DOI: 10.12659/AJCR.926785

Available online: 2020-08-18

Published: 2020-09-24


BACKGROUND: In corona virus disease 2019 (COVID-19), which emerged in December 2019 and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), most case presentations have been related to the respiratory tract. Several recent studies reveal that angiotensin-converting enzyme 2 (ACE2), which was found in the target cells of the virus, is highly expressed in the lungs, small bowel, and vasculature.
CASE REPORT: A 29-year-old male construction worker from India presented with left-sided colicky abdominal pain. He tested positive for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription-polymerase chain reaction (RT-PCR). Isolated superior mesenteric vein thrombosis was diagnosed by CT (computed tomography) scan. He was managed by anti-coagulants and clinically improved.
CONCLUSIONS: This case report indicates that isolated venous thrombosis of the abdominal vessels without concurrent arterial thrombosis can be a complication of the hyper-coagulability state in COVID-19 patients. Hence, early evaluation of abdominal vessels in covid-19 patients who present with any abdominal symptoms should be considered, especially when found to have an elevated D-dimer level, as early treatment of thrombosis with low-molecular-weight heparin can have a significant impact on the therapeutic outcome.

Keywords: COVID-19, SARS Virus, Venous Thrombosis