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Medical Science Monitor Basic Research


Sudden Esophageal Necrosis and Mediastinitis Associated with Invasive Candidiasis: A Case Report

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care, Rare disease

Maria J. Riascos, Fredy A. Watts-Pajaro, Francisco L. Uribe-Buritica, José J. Serna, Oscar Rojas, Virginia Zarama Cordoba

Colombia Department of Emergency Medicine, Universidad ICESI (ICESI University), Cali, Colombia

Am J Case Rep 2021; 22:e928394

DOI: 10.12659/AJCR.928394

Available online: 2021-05-21

Published: 2021-06-28


BACKGROUND: Esophageal necrosis is a rare entity characterized by the presence of extensive circumferential necrosis of the esophagus. It generally affects older adults who have associated chronic pathologies and has a reported mortality rate of approximately 32%. Most patients with esophageal necrosis have a complex clinical course.
CASE REPORT: We present the case of a 37-year-old man with idiopathic chronic renal failure who presented to the Emergency Department with sudden esophageal necrosis and mediastinitis, associated with invasive candidiasis. Diagnosis was challenging owing to the rarity of the condition. The patient required intensive care management and multiple surgical procedures.
CONCLUSIONS: Esophageal necrosis is an uncommon pathology that can be fatal because of associated complications. Its pathophysiology is unclear, and its treatment is based on the control of local injury and signs and symptoms. Acute esophageal necrosis associated with invasive Candida sp. infection is even more infrequent, with only a few cases reported in the literature.

Keywords: Candida albicans, Emergency Service, Hospital, Esophageal Diseases, Necrosis