07 December 2021 : Case report
[In Press] Combination of Adenomyoepithelioma and Adenoid Cystic Carcinoma of the Breast: A Case Report of an Uncommon Histopathological Entity
Rare coexistence of disease or pathologyAntigoni Spyrou1ABCDEF, Anastasios Katsourakis1ABCDEF, Dimitrios Chytas2ABCDE, George Komsis3ABCDE, Iosif Chatzis1ABCDEF, Pavlina Pantelidou4ABCDEF, Sergios Konstantinidis1ABCDEF, George Noussios3ABCDF
Am J Case Rep In Press; DOI: 10.12659/AJCR.934391
Available online: 2021-12-07, In Press, Corrected Proof
Publication in the "In-Press" formula aims at speeding up the public availability of the pending manuscript while waiting for the final publication. The assigned DOI number is active and citable. The availability of the article in the Medline, PubMed and PMC databases as well as Web of Science will be obtained after the final publication according to the journal schedule
Adenomyoepithelioma and adenoid cystic carcinoma are uncommon types of breast tumors. Adenoid cystic carcinoma accounts for 0.1% of breast neoplasms and typically presents as a tender breast tumor, mostly in the subareolar area. Adenoid cystic carcinoma usually appears in women in the fifth or sixth decade of life and predominantly presents as a mixed tumor, with cribriform, tubular, and solid growth characteristics. Adenomyoepithelioma of the breast shows epithelial and smooth muscle characteristics. Adenomyoepithelioma rarely goes through malignant transformation and is an uncommon type of benign breast tumor.
Our study reviews the current published literature regarding the combination of these 2 rare neoplasms of the breast and shows a rare case of a 48-year-old woman with a combination of adenoid cystic carcinoma and adenomyoepithelioma.
The combination of adenoid cystic carcinoma and adenomyoepithelioma should be part of the differential diagnosis in breast cancer. More research is needed regarding the optimal therapy, which is currently surgical excision.
Keywords: Adenomyoepithelioma; Breast Neoplasms; Carcinoma, Adenoid Cystic; Mastectomy; Mastectomy, Segmental
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