Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

19 January 2022 : Case report  Romania

A Case of Giant Mesenchymal Uterine Tumor: Lipoleiomyoma

Rare disease

Madalina Bosoteanu12A, Raluca Ioana Vodă ORCID logo34E*, Cristian Ionut Orasanu34E, Mariana Aschie35D, Manuela Enciu32F, Gabriela Izabela Baltatescu ORCID logo34B

DOI: 10.12659/AJCR.934913

Am J Case Rep 2022; 23:e934913


BACKGROUND: Uterine lipoleiomyoma is a rare benign tumor composed of varying proportions of smooth muscle fibers and mature adipocytes, without identification of hemorrhage, necrosis, or cyto-architectural atypia. It is part of the leiomyomas category, with an incidence of 0.03-0.2%. The pathogenesis of this lesional category is still unclear, but there are several theories that could explain the occurrence. Magnetic resonance imaging is the most useful diagnostic imaging method. There are a number of pathologies whose exclusion is necessary, with the differential diagnosis being made mainly based on microscopic examination and completed with immunohistochemical tests. Their treatment, when necessary, is surgical, with an excellent post-therapeutic evolution and prognosis.

CASE REPORT: We present the case of an elderly, postmenopausal patient who presented with abdominal pain, abnormal vaginal bleeding, and pollakiuria. The associated pathologies of the patient correspond to those mentioned in the literature, the particularities of the case being given by the large size of the tumor and the association with 2 other typical leiomyomas. Immunohistochemical markers used to exclude other diagnoses (desmin, h-caldesmon, S100, calretinin, MDM2, CD34) confirmed the diagnosis of uterine lipoleiomyoma. Because the patient was symptomatic and a large nodular mass was identified by ultrasound, surgical treatment was performed.

CONCLUSIONS: Although it is a benign lesion with an excellent prognosis, the pathogenetic mechanisms are not fully known. Theories of pathogenesis range from misplacing embryonic adipocytes to connective tissue fatty degeneration, and further studies are needed to establish the origin of this lesion.

Keywords: Adipocytes, Myocytes, Smooth Muscle, Postmenopause, Uterus



18 January 2022 : Case report  Italy

Sickle Cell Trait and SARS-CoV-2-Induced Rhabdomyolysis: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.934220  

11 January 2022 : Case report  Oman

Myocarditis, Pulmonary Hemorrhage, and Extensive Myositis with Rhabdomyolysis 12 Days After First Dose of P...

Am J Case Rep In Press; DOI: 10.12659/AJCR.934399  

12 January 2022 : Case report  USA

Guillain-Barré Syndrome After Ad26.COV2.S Vaccination

Am J Case Rep In Press; DOI: 10.12659/AJCR.935275  

10 January 2022 : Case report  Philippines

Pulmonary Function and Chest Computed Tomography (CT) Scan Findings After Antifibrotic Treatment for COVID-...

Am J Case Rep In Press; DOI: 10.12659/AJCR.934830  

In Press

19 Jan 2022 : Case report  Latvia

Rare Case of Hodgkin Lymphoma Transformation into Diffuse Large B-Cell Lymphoma with Atypical Spread Epidur...

Am J Case Rep In Press; DOI: 10.12659/AJCR.935014  

19 Jan 2022 : Case report  Saudi Arabia

Autoimmune Hemolytic Anemia – Rare Complication of Brucellosis in a Saudi Woman: A Case Report and Literatu...

Am J Case Rep In Press; DOI: 10.12659/AJCR.935187  

18 Jan 2022 : Case report  Saudi Arabia

Annular Epidermolytic Ichthyosis Mimicking Greither Disease: A Case Report and Literature Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.935393  

18 Jan 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

Am J Case Rep In Press; DOI: 10.12659/AJCR.935250  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

24 Jul 2020 : Case report  Canada

Symptoms of Pleurisy as the Initial Presentation of COVID-19

DOI :10.12659/AJCR.925775

Am J Case Rep 2020; 21:e925775

09 Dec 2021 : Case report  USA

Left Ventricular Assist Device Pump Thrombosis in a Patient Treated with Apixaban

DOI :10.12659/AJCR.934787

Am J Case Rep 2021; 22:e934787

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923