Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

13 July 2026 : Case report  USA

Exercise-Induced Complete Heart Block and Sinoatrial Exit Block in Baseline Bifascicular Block

Unusual or unexpected effect of treatment, Rare disease

Asher Gorantla ABEF 1, Peter Cwalina ORCID logo DEF 2*, Aleksander Łuniewski BE 3, Ahmad Jallad DE 4, Natalia Turkiewicz ORCID logo ABCDEF 5, Adam S. Budzikowski ORCID logo ADEF 4

DOI: 10.12659/AJCR.949566

Am J Case Rep 2026; 27:e949566

Abstract

0:00

BACKGROUND: Bifascicular block is typically asymptomatic and incidentally diagnosed, yet it may progress to advanced conduction disturbances. In patients with unexplained syncope and conduction abnormalities, exercise stress testing can diagnose transient conduction disease. While not routinely indicated for known atrioventricular block, stress testing may clarify etiology in patients without resting high-grade block. We present a case of syncope in a patient with bifascicular block, in whom exercise stress testing revealed complete atrioventricular block and sinoatrial exit block.

CASE REPORT: A 72-year-old man with chronic right bundle branch block and left anterior fascicular block presented with recurrent exertional syncope. Baseline electrocardiogram revealed bifascicular block, prompting exercise stress testing. During transition from Stage 1 to Stage 2 of the Bruce protocol, he developed transient complete atrioventricular block and near-syncope, followed by Mobitz II atrioventricular block and repetitive sinoatrial Wenckebach block during recovery. Computed tomography coronary angiography showed no obstructive lesions. A dual-chamber permanent pacemaker was subsequently implanted. Follow-up showed minimal pacing, and resolution of symptoms.

CONCLUSIONS: This case highlights the diagnostic utility of exercise stress testing in patients with conduction abnormalities and unexplained syncope. The concurrent occurrence of atrioventricular block and sinoatrial exit block during stress testing is rare. This directly guided our management. Stress testing reproduced transient high-grade atrioventricular block and sinoatrial exit block, and preceded progressive conduction deterioration over 4 years, to near-continuous ventricular pacing. Stress testing provides symptom-electrocardiogram correlation; the provoked atrioventricular block may indicate advanced conduction-system disease progression, and documentation of syncope with high-grade block supports timely pacing.

Keywords: atrioventricular block, Sinoatrial Block, Exercise Test, Cardiac Electrophysiology, Bundle-Branch Block, Pacemaker, Artificial, Electrocardiography

Add Comment 0 Comments

In Press

Case report  China

Coexistence of Multiple Myeloma, Mast Cell Hyperplasia, and Low-Level Myeloid Blastocytosis: A Report of a ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.952005  

Case report  Saudi Arabia

Primary Small Cell Neuroendocrine Carcinoma of the Breast in a 75-Year-Old Woman With Aggressive Recurrence...

Am J Case Rep In Press; DOI: 10.12659/AJCR.952443  

Case report  USA

Single-Dose Nivolumab as a Trigger of Myocarditis, Myositis, and Myasthenia Gravis Overlap Syndrome With La...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953173  

Case report  Japan

A 73-Year-Old Man With a Late Isolated Brain Metastasis of Clear Cell Renal Cell Carcinoma Following a Dura...

Am J Case Rep In Press; DOI: 10.12659/AJCR.953192  

Most Viewed Current Articles

07 Dec 2021 : Case report  USA 22,322,332

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

06 Dec 2021 : Case report  Brazil 174,155

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

21 Jun 2024 : Case report  China (mainland) 119,679

Intracranial Parasitic Fetus in a Living Infant: A Case Study with Surgical Intervention and Prognosis Anal...

DOI :10.12659/AJCR.944371

Am J Case Rep 2024; 25:e944371

0:00

07 Mar 2024 : Case report  USA 64,608

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923