13 July 2020: Articles
Desmoplastic Small Round Cell Tumor of Pancreatic Origin in a Young Child: A Case Report and Review of Literature
Challenging differential diagnosis, Management of emergency care, Patient complains / malpractice, Rare disease, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons
Daniyah Saleh A , Sahar Al-Maghrabi A , Haneen Al-Maghrabi A , Jaudah Al-Maghrabi A*DOI: 10.12659/AJCR.922762
Am J Case Rep 2020; 21:e922762
Table 1. Summary of reported cases of primary pancreatic desmoplastic small round cell tumor including the present case.
| Pt. No. | Author [reference] | Age/sex | Presentation | Duration of symptoms/complaint | Metastasis | Therapy | Outcome |
|---|---|---|---|---|---|---|---|
| 1 | Present case | 9 years/Male | Abdominal pain | 3 months | Mesenteric lymph nodes | Distal pancreatectomy, splenectomy, splenic flexure, and colon segment resection+six cycles of non-RMS chemotherapy | Recurrence at 7 months |
| 2 | Bismar TA et al. 2004 []6 | 31 year/Female | Enlarging abdomen | 2 months | Smaller nodules on the peritoneal surfaces, bilaterally on ovarian surfaces and pelvis | Subtotal pancreatectomy with partial stomach resection | NA |
| 3 | Seshadri A et al. 2014 []7 | 40 year/Female | Abdominal pain | 2 years | peritoneal deposits confined to lesser omentum and anterior surface of transverse mesocolon | Distal pancreatectomy, splenectomy, and left upper quadrant peritonectomy+three cycles of chemotherapy (MESNA, etoposide based) | No recurrence at 6 months |
| 4 | Subasinghe D et al. 2014 []8 | 24 year/Male | Rapidly progressive obstructive jaundice associated with abdominal pain | 1 month | No evidence of peritoneal or liver metastases | Whipple’s procedure+adjuvant combination chemotherapy (vincristine, cyclophosphamide, doxorubicin, ifosfamide and etoposide) | No recurrence at 6 months |
| 5 | Qureshi SS et al. 2011 []9 | 16 year/Female | Abdominal lump | 1 month | Negative | Chemotherapy (9 weeks), then distal pancreatectomy with splenectomy, transverse colon resection was performed | No recurrence at 14 months |
| 6 | Albiruni R et al. 2007 []10 | 35 year/Female | Progressive abdominal pain and weight loss | 5 months | At least two large liver metastases | Vinorelbine/cyclophosphamide | NA |
| * NA – not available. | |||||||