06 July 2020>: Articles
Nesidioblastosis Associated with Pancreatic Heterotopia as a Differential Diagnosis of Hypoglycemia: A Literature Review and Case Report
Challenging differential diagnosis, Rare coexistence of disease or pathology
Aline A. Lopes A* , Ana C. Miranda B , Marcelo S. Maior B , Roberto V. de Mello B , Francisco Bandeira ADOI: 10.12659/AJCR.922778
Am J Case Rep 2020; 21:e922778
Table 2. Main characteristics of the selected reports.
Authors and year | Age and gender | Clinical presentation | Imaging and surgery aspects | Treatment |
---|---|---|---|---|
Kang H.: The Journal of Gastroenterology. 2014 []14 | Female, 35 years old | Recurrent acute pancreatitis | Glucagon-positive 17 mm pancreatic tail neuroendocrine tumor with areas of nesidioblastosis in ectopic localization of pancreatic islets in central acinar areas | Distal pancreatectomy |
Yasoshima H.: Pathology International. 2001 []15 | Female, 5 months | Dyspnea, abdominal distension and hematemesis 30 hours after birth | Autopsy with jejunum nodule measuring 30×20×20 mm, corresponding to ectopic pancreatic tissue with topic and ectopic pancreas nesidioblastosis | Intensive care support with hypertonic glucose infusion |
Schier F.: Pediatric Surgery International. 2000 []16 | Child (undefined gender), 30 months | Severe hypoglycemia | Meckel’s diverticulum enlarged, measuring 45 mm. Presence of gastric and pancreatic tissue in Meckel’s diverticulum, with areas of nesidioblastosis in pancreatic tissue in Meckel’s diverticulum | Meckel’s diverticulum resection |
Seki S.: Pediatrics International. 1990 []17 | Newborn (undefined gender), 6 hours of life | Severe hypoglycemia, seizures and cyanosis | Laparotomy with normal pancreas. Tumor finding in the duodenum anterior wall, measuring 8×5×5 mm, corresponding to ectopic pancreatic tissue with areas of nesidioblastosis | Resection of tumor in duodenum and 75% of pancreas |