18 September 2020: Articles
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Induced by Long-Term Use of Citalopram and Short-Term Use of Naproxen
Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology
Chia-Yu Chiu B* , Amara Sarwal E , Rehan Azhar Munir A , Michael Widjaja C , Amna Khalid B , Rajan Khanna ADOI: 10.12659/AJCR.926561
Am J Case Rep 2020; 21:e926561
Table 1. Laboratory values and management of the patient.
| 4 years ago | 10 months ago | Day 1 | Day2 | Day 3 | Day 5 | Day 7 | Day 10 | Day 14 | Day 30 | Day 90 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium (mmol/L) | 140 | 129 | 113 | 112 | 113 | 118 | 128 | 131 | 133 | 137 | 136 |
| Potassium (mmol/L) | 4.7 | 4.5 | 4.7 | 4.4 | 4.2 | 4.2 | 4.9 | 4.7 | 4.5 | 4.4 | 4.6 |
| Chloride (mmol/L) | 100 | 91 | 76 | 77 | 77 | 82 | 90 | 93 | 97 | 95 | 97 |
| BUN (mg/dL) | 15 | 10 | 7 | 6 | 7 | 10 | 13 | 10 | 17 | 23 | 19 |
| Creatinine (mg/dL) | 0.8 | 0.6 | 0.47 | 0.47 | 0.47 | 0.48 | 0.52 | 0.65 | 0.97 | 1 | 1 |
| Uric acid (mg/dL) | 1.8 | 2.8 | |||||||||
| Serum osmolality (mOsm/kg) | 240 | 271 | |||||||||
| Intervention | Stop Citalopram and Naproxen | Start Meloxicam 15 mg daily | |||||||||
| Fluid intake | limited fluid intake to 1 L per day | limited fluid intake to 0.5 L per day | |||||||||
| Sodium tablet | Sodium tablet 2 g twice a day | ||||||||||