30 July 2021>: Articles
A 40-Year-Old Man with Sarcoidosis and Factor V Leiden Thrombophilia Presenting with Deep Vein Thrombosis and Pulmonary Thromboembolism
Rare coexistence of disease or pathology
Anna Goljan-Geremek A* , Elżbieta Puścińska C , Witold Tomkowski D , Paweł Śliwiński DDOI: 10.12659/AJCR.932286
Am J Case Rep 2021; 22:e932286
Table 1. Results of the patient’s thrombophilia evaluation tests, from which a heterozygous mutation of the factor V Leiden gene was discovered.
Diagnostic test | Result | Normal values | Comment |
---|---|---|---|
Prothrombin time | 10.87 s | 8.8–13.2 s | Normal value |
Prothrombin index | 97.5% | 80–120% | Normal value |
Thrombin time | 18.38 s | Normal value | |
Fibrinogen (Claus method) | 3.05 g/l | 2–5 g/l | Normal value |
APTT Partial Thromboplastin Time | 28.93 s | 25–33 s | Normal value |
Lupus anticoagulant | Negative | ||
Factor VIII | 102.76% | 50–150% | Normal value |
Antithrombin activity (chromogenic assay, anti IIa) | 99.75% | 79–112% | Normal value |
Antithrombine activity (chromogenic assay, anti Xa) | 95.96% | 83–118 | Normal value |
Protein C activity (chromogenic assay) | 141.08% | 70–140 | ↑ |
Protein S antigen free | 104.37% | 67.5–139% | Normal value |
Activated protein C resistance APCR Test | 0.5 | 0.7–1.2 | ↓ |
Anticardiolipin antibodies IgG | 2.2 | Normal value | |
Anticardiolipin antibodies IgM | 1.5 | Normal value | |
Beta2glycoprotein antibodies IgG | 2.7 | Normal value | |
Beta2glycoprotein antibodies IgM | 0.7 | Normal value | |
Gene V Leiden mutation | Present, heterozygous | ||
The C677T mutation in the MTHFR gene | Absent, genotype GG |