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25 November 2021: Articles

A Case of Paroxysmal Cold Hemoglobinuria Possessing Moderate Paroxysmal Nocturnal Hemoglobinuria-Type Erythrocytes

Challenging differential diagnosis

Takeshi Sugimoto E* , Eri Masui B , Shinya Ohata B , Hideaki Goto D , Takako Tomita C , Hiromi Hashimoto F , Yoshihiro Bouike C

DOI: 10.12659/AJCR.933102

Am J Case Rep 2021; 22:e933102

Table 1. The results of the serological test.

Serological testResult
Blood typeB type
Rh typeCcDEe
Antibody screening test (column technique)(−)
  Saline test (normal saline)(−)
  Saline test (cooled saline)(+)
Antibody identification testAnti-P1
Direct antiglobulin test
  Broad spectrum(−)
  Anti-IgG(−)
  Anti-C3d(−)
Indirect antiglobulin test(−)
Donath-Landsteiner test(+)
Cold agglutinin (titer)32
Haptoglobin (mg/dL)
PNH-type cells
  Granulocytes
  Type III (%)73.0
  Type II+III (%)73.3
  Erythrocytes
  Type III (%)16.9
  Type II+III (%)19.6

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923