08 November 2021: Articles
Gestational Diabetes Mellitus Complicated by Hemolysis, Elevated Liver Enzymes, and Low Platelet Count After Decreased Need for Insulin: 2 Cases
Unusual clinical course, Diagnostic / therapeutic accidents
Yoshimasa Kawarai A* , Shogo Kaneko B , Masataka Kagimoto B , Ayaka Kaneko B , Naoki Ichii B , Kaoru Kakinuma B , Koyomi Saito B , Motomasa Ihara B , Toshiyuki Kakinuma B , Michitaka Ohwada B , Hirokazu Tanaka BDOI: 10.12659/AJCR.933460
Am J Case Rep 2021; 22:e933460
Table 1. Baseline characteristics of the 30 patients with GDM.
| Case no. | Age (y) | Parity (n) | Height (cm) | Weight before pregnancy (kg) | BMI (kg/m2) | HbA1c (%) | HOMA-IR | Obstetric history and complications |
|---|---|---|---|---|---|---|---|---|
| 1 | 42 | 0 | 155.5 | 76 | 31.4 | 5.5 | 1.34 | Stillbirth with multiple malformations |
| 2 | 38 | 0 | 148 | 54 | 24.6 | 5.4 | 1.28 | Preexisting epilepsy |
| 3 | 34 | 2 | 162 | 83 | 31.6 | 5.6 | 1.4 | Cesarean section |
| 4 | 28 | 1 | 153 | 43 | 18.3 | 4 | 4.36 | Cesarean section, preexisting hyperthyroidism |
| 5 | 40 | 0 | 164 | 45 | 16.9 | 5.2 | 1.4 | In vitro fertilization, myoma enucleation |
| 6 | 34 | 0 | 154.5 | 67.5 | 28.2 | 5.6 | 2.3 | |
| 7 | 28 | 2 | 159.1 | 49 | 19.3 | 5.4 | 2.69 | |
| 8 | 28 | 0 | 153 | 57 | 24.3 | 5.2 | 1.55 | In vitro fertilization |
| 9 | 36 | 0 | 161 | 57 | 21.9 | 5.2 | 1.94 | |
| 10 | 32 | 1 | 164 | 70 | 26 | 6 | 1.05 | In vitro fertilization, cesarean section |
| 11 | 42 | 0 | 164 | 111 | 41.2 | 5.6 | 2.75 | |
| 12 | 40 | 0 | 156.3 | 48 | 19.6 | 5.2 | 7.67 | In vitro fertilization |
| 13 | 27 | 0 | 152 | 57 | 24.6 | 5.8 | 2.61 | |
| 14 | 33 | 1 | 169 | 69 | 24.1 | 6.2 | 3.54 | Cesarean section |
| 15 | 30 | 1 | 158 | 45 | 18 | 5.2 | 0.79 | |
| 16 | 33 | 0 | 157.5 | 46 | 18.5 | 5.1 | 0.54 | |
| 17 | 32 | 3 | 152.5 | 64 | 27.5 | 5.7 | 1.68 | |
| 18 | 29 | 2 | 157 | 50 | 20.2 | 5.1 | 1.39 | |
| 19 | 30 | 0 | 158 | 74 | 29.6 | 5.4 | 0.91 | In vitro fertilization |
| 20 | 30 | 1 | 164 | 52 | 19.3 | 5.5 | 0.7 | |
| 21 | 33 | 2 | 150 | 55 | 24.4 | 5.1 | 1.44 | |
| 22 | 32 | 0 | 147.2 | 71 | 32.7 | 5.8 | 2.63 | |
| 23 | 39 | 2 | 152.5 | 63.5 | 27.3 | 5.7 | 2.19 | |
| 24 | 35 | 0 | 158.5 | 80 | 31.8 | 5.4 | 2.72 | GDM in previous pregnancy |
| 25 | 38 | 0 | 161 | 47 | 18.1 | 5.2 | 1.34 | |
| 26 | 21 | 0 | 160 | 63 | 24.2 | 5.8 | 1.74 | |
| 27 | 23 | 2 | 160 | 49 | 19.1 | 6.1 | 4.22 | |
| 28 | 35 | 0 | 156.6 | 57 | 23.2 | 5.6 | 1.03 | |
| 29 | 36 | 0 | 164.9 | 54 | 19.8 | 5.2 | 0.78 | |
| 30 | 35 | 0 | 153.2 | 60 | 25.5 | 5.5 | 0.78 | Preexisting optic neuromyelitis |
| Average | 33.1±5.1 | 157.5±5.2 | 60.6±14.3 | 24.4±5.6 | 5.4±0.4 | 2.03±1.4 | ||
| GDM – gestational diabetes mellitus; BMI – body mass index; HbA1c – hemoglobin A1c; HOMA-IR – homeostatic model assessment of insulin resistance. | ||||||||