26 December 2021: Articles
Parathyroid Carcinoma: A Rare Endocrine Malignancy
Rare disease
Nádia Mourinho Bala B* , José Maria Aragüés E , Sílvia Guerra E , Nuno Cordeiro Raposo B , Cristina Valadas EDOI: 10.12659/AJCR.934221
Am J Case Rep 2021; 22:e934221
Table 1. Demographic, biochemical data, pathological findings, and follow-up in 3 patients with parathyroid carcinoma.
| Case | Sex, age | Preoperative PTH (pg/mL) | Preoperative calcemia (mg/dL) | Surgical procedure | Pathological features | Follow-up |
|---|---|---|---|---|---|---|
| 1 | M, 30 | 1396 | 19.0 | Left inferior PTX | Angioinvasive | Disease free (5-year follow-up) |
| 2 | M, 45 | 310,1 | 11.0 | Right inferior PTX, total thyroidectomy | Capsule and adjacent soft tissues invasion, Ki-67 15% | Disease free (6-month follow-up) |
| 3 | M, 38 | 1953 | 19.1 | Left superior PTX, total thyroidectomy | Capsule and adjacent soft tissues invasion, Ki-67 30–60% | Cutaneous and lung metastasis, 5 and 6 years after surgery, respectively |
| PTH – parathyroid hormone; PTX – parathyroidectomy; M – male sex. | ||||||