Secondary Hemophagocytic Lymphohistiocytosis in a Neonate with SARS-CoV-2 Infection

28 January 2022: Articles

Challenging differential diagnosis, Rare disease, Clinical situation which can not be reproduced for ethical reasons

Hasan Zuhair El-Isa ^A* , Osama As’ad Khader ^A , Mustafa Khader ^A , Bahaa Abed Ashour ^A , Muayad Imad Azzam ^A , Eman Farouk Badran ^A

DOI: 10.12659/AJCR.934839

Am J Case Rep 2022; 23:e934839

Table 1. CBC levels details from day 2 to day 40 of life.

Day of life	Hb (g/dl)	RBC (million/mm3)	WBC (cell/mm3)	Lymphocyte (%)	Lymphocyte count (cell/mm3)	Neutrophils (%)	ANC (cell/mm3)	Platelets ×109/L
Normal ranges	13–20	5.1–5.3	5000–21 000	48	2400– 10 080	40–80	2000–16 800	150 000–450 000
2	17.0	5.59	1.96	44.3	0.87	41.1	0.8	101
4	11.5	4.16	0.43	28.0	0.12	3.3	0.014	124
5	12.7	4.51	0.61	38.0	0.23	8.0	0.048	104
7	11.9	4.41	0.70	36.0	0.25	26.0	0.180	216
10	10.8	3.78	0.86	66.0	0.57	24.0	0.200	365
17	10.7	4.70	0.73	47.0	0.34	0.0	0.000	458
21	8.8	3.19	0.88	46.0	0.40	1.0	0.008	210
23	9.0	3.28	1.14	44.0	0.50	4.0	0.045	186
28	6.2	2.17	1.02	70.0	0.71	20.0	0.200	110
29	10.8	3.76	1.08	72.0	0.78	14.0	1.080	80
34	7.8	2.78	1.00	80.0	0.80	10.0	0.100	98
36	9.7	3.17	0.89	38.0	0.34	6.0	0.053	44
37	11.4	3.70	0.58	73.4	0.43	14.1	0.080	40
38	11.5	3.90	0.33	70.0	0.23	20.0	0.066	35
39	9.4	3.07	0.47	33.0	0.16	12.0	0.056	58
40	8.1	2.71	0.35	60.0	0.21	24.0	0.084	40
Hb – hemoglobin level; RBC – red cell count; WBC – weight cell count; ANC – absolute neutrophil count.