10 January 2022>: Articles
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV) Registry
Unusual clinical course, Unusual or unexpected effect of treatment
Christian Schumann * , Franz Heigl B , Imanuel J. Rohrbach B , Ahmed Sheriff A , Lutz Wagner B , Florian Wagner C , Jan Torzewski **DOI: 10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
Table 1. Patient characteristics.
Patient | Age | Sex | Concomitant diseases | Duration of symptoms before hospital admission (d) | Oxygen supply, intubation, ventilation duration (d) | Hospital length of stay (d) | PCR, C(t), mutation analysis | Antibiotic therapy | Further issues |
---|---|---|---|---|---|---|---|---|---|
1 | 37 | F | Immune deficiency, multiple sclerosis | ca. 21 | 5 (NIV) | 7 | SARS-CoV-2-VOC, C(t) 28.2, B.1.1.7 (Alpha) | .. | COVID reactivation under Rituximab therapy |
2 | 60 | M | Arterial hypertension, coronary heart disease, obesity, DM type II | 2 | 16 (NIV) | 15 | SARS-CoV-2-VOC, C(t) 25.8, B.1.617.2 (Delta) | .. | .. |
3 | 57 | M | Arterial hypertension, emphysema | 11 | 9 (NIV) | 9 | SARS-CoV-2-VOC, C(t) 31.5, B.1.617.2 (Delta) | From d 1 to d 6 | .. |
4 | 54 | M | Arterial hypertension, obesity | 9 | 10 (NIV) | 9 | SARS-CoV-2, no mutation analysis | .. | .. |
5 | 57 | F | Coronary heart disease, ischemic cardiomyopathy, allergic diathesis | 7 | 4 (intubation), 7 (NIV) | 21 (15-21: social reasons) | SARS-CoV-2-VOC, C(t) 25.2, B.1.617.2 (Delta) | From d 11 to d 17 | Secondary bacterial pneumonia (from d 11 onwards) |
6 | 58 | M | .. | 0 | 8 (Intubation), 12 (NIV) | 21 | SARS-CoV-2-VOC, C(t) 19.9, B.1.617.2 (Delta) | From d 3 to d 8 and from d 9 to d 21 | pneumonia, anxious depressive adjustment disorder under COVID pneumonia |
7 | 43 | M | Sleep apnoea syndrome, arterial hypertension | 8 | 8 (NIV) | 8 | SARS-CoV-2-VOC, C(t) 28.2, B.1.617.2 (Delta) | .. | .. |
Table shows age, sex, concomitant diseases, respiratory supply, hospital length of stay, PCR, antibiotic therapy and further issues in our 7 patients. All patients had documented SARS-CoV-2-induced pneumonia and respiratory failure. DM – diabetes mellitus; C(t) – crossing threshold; PCR – polymerase chain reaction; SARS-CoV-2-VOC – severe-acute-respiratory-syndrome-coronavirus-2-variant of concern). |