23 May 2023>: Articles
A Case of an 82-Year-Old Man with a Spinal Extradural Malignant Ossifying Fibromyxoid Tumor
Challenging differential diagnosis, Rare disease
Qiqi Lu B* , Chi Long Ho ADOI: 10.12659/AJCR.939408
Am J Case Rep 2023; 24:e939408
Table 1. Summary of previous cases of spinal ossifying fibromyxoid tumors (OFMT) reported in the literature.
First author, year (reference) | Age (year-old)/gender | Spinal involvement | Treatment | Prognosis |
---|---|---|---|---|
Cha (2008) []10 | 37/F | Locally aggressive, invaded L5 vertebra with epidural and pelvic/sacral extension | Pre-op arterial embolization, L5 vertebra corpectomy, subtotal tumor resection and posterior fusion | Post-op RT 25 fraction after surgery. No evidence of tumor recurrence over 5y follow-up |
Jaypal (2010) []8 | 70/M | Paraspinal mass centred at L2 vertebra with epidural invasion via neural foramen | Tumor debulking followed by post-op RT 70 Gy | Remnant tumor enlarged 15-mths after debulking with paraspinal extension. Following second surgery, new recurrence after 4-mths. Patient refused further treatment |
De Wandeler (2019) []9 | 37/F | Soft tissue mass centered at right trapezius muscle with extension to paraspinal muscles and central canal, compressing spinal cord and nerve roots | Surgical resection of primary tumor | Multiple recurrences were unsucessfully managed despite repeated surgery, RT and chemotherapy |
Lu (2022) (current case) | 82/M | Extradural tumor with cord compression | Tumor debulking followed by locoregional RT | Intracranial metastasis to cerebellopontine angles and ‘drop’ metastasis to the conus medullaris at 17-mths, and deceased 21-mths after initial tumor surgery |
F – female; M – male; mth – months; RT – radiation therapy; y – years. |