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12 October 2023: Articles

Successfully Managing Severe Anemia in a Trauma Patient Who Refused Blood Transfusion: A Case Report

Management of emergency care

Irene F. Sanchez A , Han-young Lee A , Jae-myeong Lee A*

DOI: 10.12659/AJCR.940326

Am J Case Rep 2023; 24:e940326

Table 1. Summary of trauma cases involving Jehovah’s Witness patients in the past 20 years.

Age/caseHemoglobin levelManagementOutcomeJournal
1. A 67-year-old male patient experienced a motor vehicular accident and sustained right-sided rib fractures, right anterior chest wall and mediastinal hematomas, left pneumothorax, bilateral pulmonary contusions, and fractures of the left distal humerus and left distal femur (2004) []11 3 g/dLIronFolic acidVitamin B12Vitamin KErythropoietinSurvivedJournal of Clinical Anesthesia
2. A 6-year-old male patient experienced a motor vehicular accident and sustained cranial depression, periorbital edema on the right, hematoma on the right thigh with femur fracture, a contusion-laceration wound on the left thigh, and scrotal region and glans penis hematoma (2006) []26 5 g/dLFolic acidVitamin KErythropoietinRight Frontal craniotomySurvivedJournal of Hematology
3. A 76-year-old female patient experienced blunt abdominal trauma, rib fractures, and grade III splenic injury (2008) []27 9 g/dLLaparoscopic SplenectomySurvivedSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
4. A 36-year-old male patient experienced severe burn encompassing 35% of the TBSA (2014) []28 8.6 g/dLVitamin KIronTranexamic acidErythropoietinFascial excision and split-thickness skin graftingSurvivedJournal of Burn Care and Research
5. A 65-year-old male patient experienced a fall and sustained multiple rib fractures, splenic rupture, and multiple intestinal ischemic perforations (2013) []12 3.5 g/dLIronVitamin B12ErythropoietinSplenectomy and Ileocecal resectionSurvivedBlood Transfusion
6. A 51-year-old female patient experienced an automobile collision and sustained bilateral femoral, tibial, and fibular fractures (2001) []29 3 g/dLIronVitamin KErythropoietinCryoprecipitateDeceasedCritical Care Nurse
7. A 23-year-old male patient crushed between two cars and sustained grade III liver laceration and active pelvic hemorrhage (2016) []30 3.9 g/dLIronErythropoietinHemopurePercutaneous pinning of pelvic fracturesSurvivedArchives of Trauma Research
8. A 39-year-old male patient experienced fall and underwent popliteal artery and vein transection after knee dislocation (2010) []31 3.4 g/dLVasopressorExternal fixationDeceasedObesity Surgery
9. A 49-year-old male patient experienced a motor vehicular accident and sustained bilateral acetabular fracture (2005) []32 8.4 g/dLErythropoietinAutologous blood transfusion (cell saver)AprotininOpen reduction and internal fixation of acetabular fractureSurvivedJournal of Orthopedic Trauma
10. A 21-year-old male patient experienced a high-speed motor vehicular accident and underwent near-total traumatic left ankle amputation and transection of superficial femoral artery and vein (2009) []33 2.7 g/dLReligion unknown preoperative: administered with PRBC, FFP, and platelet concentratePostoperative: CryoprecipitateIronVitamin KErythropoietinSurvivedJournal of Trauma and Acute Care Surgery
11. A 44-year-old female patient experienced a motor vehicular collision and sustained subarachnoid hemorrhage, bilateral pulmonary contusion, rib fractures, and grade I splenic laceration (2002) []34 3.2 g/dLIronErythropoietinPolyHemeSurvivedThe New England Journal of Medicine
12. A 44-year-old male patient experienced impalement injury with 2 iron rods penetrating the thorax and 1 rod penetrating the thoracolumbar area (2005) []35 3.4 g/dLErythropoietinCrystalloidsSurvivedThe Journal of Thoracic and Cardiovascular Surgery
13. A 21-year-old male patient experienced a vehicular accident and developed a degloving injury to the left forearm and abdomen and intracranial hemorrhage (2009) []24 3.2 g/dLReligion unknown preoperative: Administered with PRBCPostoperative: Vitamin KErythropoietinFactor VIIaHemopureDeceasedThe Journal of AABB Transfusion
14. A 23-year-old male patient experienced a motor vehicular accident and sustained grade III liver injury, multiple rib fracture, and pelvic fracture (2008) [] 4.6 g/dLIronVitamin KErythropoietinHemopureSurvivedJournal of Clinical Anesthesia
15. A 24-year-old male patient experienced burns encompassing 60% of the TBSA (2004) []36 4.4 g/dLIronErythropoietinFFPSurvivedBurns
16. A 5-year-old female patient experienced a lawnmower injury with multiple open fracture of the left foot and ankle (2008) []37 4.3 g/dLVitamin KErythropoietinSurvivedJournal of Pediatric Anesthesia
17. A 32-year-old female patient experienced a high-speed vehicular accident and sustained grade 4 spleen injury, bilateral rib fractures, left humeral and femoral fracture, and multi-level spinous process fracture (2011) [] 2.9 g/dLIronVitamin B12Folic acidErythropoietinFactor VIIaCryoprecipitateHemopureSurvivedThe Medical Journal of Australia
18. A 71-year-old male patient covered in soil and sustained bilateral multiple rib fractures, T10 compression fracture and left iliac wing fracture (2022)2.5 g/dLFerrous sulfate Iron isomaltosideFolic acidErythropoietinVitamin KNorepinephrineHydrocortisoneVasopressinMethylene BlueSurvivedAmerican Journal of Case Reports [current case]
Hemopure – hemoglobin-based oxygen carrier; PolyHeme – first human polymerized hemoglobin product;
* lactic acid – 4.3 mmol/L;
** lactic acid – 3.9 mmol/L; PRBC – packed red blood cell; FFP – fresh frozen plasma; TBSA – total body surface area.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923