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18 August 2023: Articles

IgG4-Related Membranous Nephropathy with Acute Nephrotic Syndrome During Successful Steroid Maintenance Treatment for Type 1 Autoimmune Pancreatitis

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology

Hiroshi Ito A , Kenji Ashida A* , Mutsuyuki Demiya B , Seiichi Motomura B , Ayako Nagayama B , Saori Kubo A , Utako Ueda A , Kei Fukami C , Masatoshi Nomura A , Tomoyuki Akashi B

DOI: 10.12659/AJCR.940707

Am J Case Rep 2023; 24:e940707

Table 1. Laboratory data on admission.

ParameterValueReference rangeParameterValueReference range
WBC, cells/μL79003,300–8,600C-reactive protein, mg/dL0.080–0.14
  Neutrophil, %73.340–74Anti-nuclear Ab, timesNegative
  Eosinophil, %3.20–6Rheumatoid factor, U/mLNegative
  Basophil, %0.80–1PR3-ANCA, U/mL
  Lymphocyte, %16.518–59MPO-ANCA, U/mL
  Monocyte, %6.20–8IgA, mg/dL17093–393
RBC count, cells×104/μL449435–555IgM, mg/dL5533–183
  Hemoglobin, g/dL14.013.7–16.83–319
  Hematocrit, %44.840.7–50.1IgG, mg/dL1380861–1747
  83.6–98.211–121
Platelet count, cells×10/μL21.515.8–34.8HBs antigenNegative
HCV AbNegative
6.6–8.1C, mg/dL10473–183
4.1–5.1C, mg/dL3011–31
AST, IU/L3013–30Anti-GAD Ab, U/mL0–5.0
ALT, IU/L2310–30
Amylase, IU/L9950–200PT/INR0.910.85–1.15
Alkaline phosphatase, IU/L8838–113APTT, second29.324–39
Blood urea nitrogen, mg/dL178–20D-dimer, μg/mL0.70–1.0
Creatinine, mg/dL0.710.65–1.07
Sodium, mmol/L141138–145
Potassium, mmol/L4.13.6–4.8RBC count/HPF0–4
Chloride, mmol/L107101–108NAG, IU/L2.90–11.5
8.8–10.1NGAL, ng/mL0–30.5
Phosphorus, mg/dL2.92.7–4.6β2MG, μg/L0–230
142–219
FPG, mg/dL10873–109
4.9–6.0
0.8–2.5
Abnormal values are presented in bold. Ab – antibody; ALT – alanine aminotransferase; APTT – activated partial thromboplastin time; AST – aspartate aminotransaminase; β2MG – beta-2 microglobulin; CPR – C-peptide immunoreactivity; FPG – fasting plasma glucose; GAD – glutamic acid decarboxylase; HbA1c – hemoglobin A1C; HBs – hepatitis B surface; HCV – hepatitis C virus; HPF – high-power field; IgA – immunoglobulin A; IgE – immunoglobulin E; IgM – immunoglobulin M; IgG – immunoglobulin G; MPO-ANCA – myeloperoxidase-anti-neutrophil cytoplasmic antibody; NAG – N-Acetyl-β-d-glucosaminidase; NGAL – neutrophil gelatinase-associated lipocalin; PR3-ANCA – proteinase 3-anti-neutrophil cytoplasmic antibody; PT/INR – prothrombin time/international normalized ratio; RBC – red blood cell; TSH – thyroid-stimulating hormone; WBC – white blood cell.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923