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07 November 2023: Articles

Paraneoplastic Neuromyelitis Optica Spectrum Disorder: A Rare Case of Advanced Breast Cancer with Intractable Nausea and Vomiting

Challenging differential diagnosis, Rare coexistence of disease or pathology

Daisuke Miyagishima A* , Toshiharu Anezaki C , Akiyo Fukuda B , Hiroki Watanabe B , Maki Hata D , Masanobu Eguchi B

DOI: 10.12659/AJCR.941808

Am J Case Rep 2023; 24:e941808

Table 2. Clinical features of neuromyelitis optica spectrum disorder (NMOSD) with positivity for aquaporin-4 antibody and herpes zoster.

AuthorYearAge, SexDermatomes of herpes zosterInterval from HZ to myelitis [days]MRI T2-high lesionVZV PCR in CSFTreatmentRelapse
Heerlein200963FLumber14C7-Th9PSL, ACV, PENo
Park201329FTh4–Th67NDPEYes
Machado201577FL4-S12C2-Th12+PSL, ACVYes
Suda201753FTh5–Th612Th1–Th7NDPulse, ACVYes
Mathew201748FC614C2–C6Pulse, ACVNo
Matsumoto201826FC4–6, Th314MO-Th7Pulse, ACV, IVIgYes
Turco202017FTh221C1-Th6Pulse, ACVNo
Eguchi202055FC4-Th314MO-C5Pulse, ACVNo
Ours51FL3–L512Th5-CMPulse, ACV
ND – no data; HZ – herpes zoster; CSF – cerebrospinal fluid; MO – medulla oblongata; CM – conus medullaris; PSL – prednisolone; pulse – methylprednisolone 1 g per day; ACV – acyclovir; PE – plasma exchange; IVIg – intravenous immunoglobulin.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923