11 January 2024: Articles
DRESS Syndrome: Renal Involvement in Two Cases – A Comprehensive Analysis and Literature Review of Improved Diagnosis and Treatment
Rare disease, Adverse events of drug therapy
Magdalena Natalia Mąsior E , Olga Maria Rostkowska A* , Agnieszka Furmańczyk-Zawiska A , Renata Wieczorek-Godlewska B , Marcin Wyzgał B , Magdalena Durlik ADOI: 10.12659/AJCR.942315
Am J Case Rep 2024; 25:e942315
Table 1. The Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) group diagnosis score for Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
| No | Yes | Unknown | Case 1* | Case 2** | |
|---|---|---|---|---|---|
| ≥ | −1 | 0 | −1 | −1 | −1 |
| ≥ | 0 | 1 | 0 | 0 | 0 |
| 0 | 1 | 0 | 0 | 0 | |
| ≥ ≥ | −1 | 1 | 0 | 2 | 2 |
| ≥ | 2 | ||||
| −1 | 1 | 0 | 2 | 2 | |
| ≥ | 0 | 1 | 0 | ||
| −1 | 0 | 0 | 0 | 1 | |
| 0 | 1 | ||||
| 2 | 1 | 2 | |||
| ≥ | −1 | 1 | −1 | 1 | 1 |
| 0 | 1 | 0 | 1 | 1 | |
| (1 point if at least 3 of the following tests are performed and are negative: HAV, HBV, HCV, mycoplasma, chlamydia, ANA, blood culture) | |||||
| Total score for DRESS diagnosis: * Case 1 – total of 6 points. ** Case 2 – total of 8 points. DRESS – Drug Reaction with Eosinophilia and Systemic Symptoms; HAV – hepatitis A virus; HBV – hepatitis B virus; HCV – hepatitis C virus; ANA – antinuclear antibodies. | |||||