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Use of combined MR angiography and MR renography in diagnosis of renal artery stenosis - preliminary report

Andrzej Cieszanowski, Marek Gołębiowski, Bartosz Symonides, Zbigniew Gaciong, Wojciech Szeszkowski

CaseRepClinPractRev 2001; 2(3):219-224

ID: 475233

The purpose of this study was to assess the quality of CE 3D multiphase MR angiography and MR renography performed after single-dose contrast material injection. Twenty patients suspected of having renal artery stenosis underwent power-injection of 30 ml of Gd-DTPA (3 ml/sec). From 10 to 360 seconds after the beginning of the injection, 3D MRA sequence was performed multiple times. Acquisition time of single phase of MR examination was 8 sec (TR = 5 ms, TE = 1.6 ms, single 7 cm thick slab with 35 partitions, 164i512 matrix). First three phases were used to obtain angiographic images. All phases were used to obtain curves of renal cortical, medullary and pyelocaliceal enhancement. Two readers evaluated quality of MRA images, as well as, quality of enhancement curves. Twenty of 22 MRA examinations were of good, 2 of fair and none of poor quality. Quality of enhancement curves was good in 20 cases. It was suboptimal in 2 cases because of irregular breath-holding. Maximum number of acquisitions per minute was 4-5. Eight accessory, 2 obstructed and 12 stenosed renal arteries were visualized. Renographic curves were abnormal in 7 patients. MRA sequence with short acquisition time enables simultaneous acquisition of angiographic images and renographic curves of good quality. With further reduction in acquisition time it may be possible to obtain more points on MR renographic curves.

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