Serial botulinum toxin a (BTX-A) injections for a fatal case of a neurogenic bladder caused by multiple sclerosis
Tomasz Drewa, Zbigniew WolskiCase Rep Clin Pract Rev 2007; 8:180-182 :: ID: 488674
Abstract
Background: Local administration of botulinum toxin A (BTX-A) inhibits presynaptic acetylcholine release. It is considered a novel option for the treatment of high pressure bladder.
Case Report: 26 old male suffering from multiple sclerosis, renal insufficiency and hiperkalimia caused by obstruction and small neurogenic bladder with urinary tract infection was presented. Live saving traetment included right percutaneus nephrostomy tube was performed. Patient refused bladder augmentation. He was treated with 3 procedures of botulinum toxin A injections (Dysport). Total dose was 1500 units. This treatment allowed to increase bladder capacity together with improvment of upper tract. Clean Intermitted Catheterization supported with α-blocker (8 mg daily) and oxibutinine (10 mg) daily allowed to prevent incontinence.
Conclusions: Botulinum toxin injections can serve as the first treatment of small spastic bladder even in cases where cystoplasty was usually considered.
Keywords: neurogenic bladder
11
In Press
12 Feb 2024 : Case report
Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...Am J Case Rep In Press; DOI: 10.12659/AJCR.942870
12 Feb 2024 : Case report
Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PETAm J Case Rep In Press; DOI: 10.12659/AJCR.941169
12 Feb 2024 : Case report
Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942839
13 Feb 2024 : Case report
Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel HematomaAm J Case Rep In Press; DOI: 10.12659/AJCR.943519
Most Viewed Current Articles
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
05 Mar 2022 : Case report
Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...DOI :10.12659/AJCR.935336
Am J Case Rep 2022; 23:e935336
02 Apr 2022 : Case report
Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...DOI :10.12659/AJCR.935743
Am J Case Rep 2022; 23:e935743