Scimago Lab
powered by Scopus
eISSN: 1941-5923
call: +1.631.629.4328
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


Get your full text copy in PDF

A Case of Seizure Revealing Fahr’s Syndrome with Primary Hypoparathyroidism

Yoo Jin Lee, Sihyung Park, Yang Wook Kim, Kang Min Park, Il Hwan Kim, Jin Han Park, Bong Soo Park

(Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea)

Am J Case Rep 2018; 19:1430-1433

DOI: 10.12659/AJCR.913382

BACKGROUND: Idiopathic basal ganglia calcification, also known as Fahr’s disease or Fahr’s syndrome, is a rare neurological disorder characterized by abnormal calcified deposits in the basal ganglia. Here, we report a case of Fahr’s syndrome with calcification of the basal ganglia due to hypoparathyroidism in a patient with seizures.
CASE REPORT: A 52-year-old male patient visited our clinic with seizures. Brain computed tomography (CT) showed bilateral symmetrical calcifications in cerebellar white matter, the corpus striatum, the posterior thalami, and the centrum semiovale of both cerebral hemispheres. He had symptoms of hypocalcemia and low parathyroid hormone levels. The patient was diagnosed with Fahr’s syndrome due to primary hypoparathyroidism. He underwent calcium supplementation and calcifediol treatment. His symptoms improved, and he was discharged from the hospital.
CONCLUSIONS: In patients with hypocalcemia accompanied by parathyroid dysfunction, neurological examination and CT should be performed to confirm abnormal intracranial calcification.

Keywords: Basal Ganglia Diseases, Hypothyroidism, Seizures

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree