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Breast Trauma and Triple-Negative Hemorrhagic Cystic Carcinoma: Management and Treatment

Maria Cotesta, Oreste Claudio Buonomo, Adriano De Majo, Gianluca Vanni, Marco Materazzo, Francesca Santori, Alessandra Vittoria Granai, Chiara Adriana Pistolese, Francesca Servadei, Susanna Finocchiaro, Erica Giacobbi, Lucia Anemona, Marco Pellicciaro

(Breast Unit, Department of Surgical Science, Tor Vergata Hospital Polyclinic, Rome, Italy)

Am J Case Rep 2020; 21:e925014

DOI: 10.12659/AJCR.925014

BACKGROUND: Breast trauma can always have diagnostic pitfalls. In the presence of a recurrent hemorrhagic cysts, cancer should always be suspected.
CASE REPORT: A 59-year-old woman noted a palpable mass after breast trauma from falling at home. Radiological exams showed a breast cyst with well-defined margins, with corpuscular and dense fluid components. First, a conservative approach was implemented. One week later, a fine-needle aspiration cytology (FNAC) of the mass showed bloody fluid without atypical cells. Three weeks later, the patient was emergently evaluated due to increased size of the lesion and anemia. To avoid further blood loss and due to suspected malignancy, an urgent surgical excision biopsy was planned. Histopathology revealed a poorly-differentiated carcinoma and the patient was treated with left modified radical mastectomy with axillary dissection. Adjuvant chemotherapy was administered. At 6-month follow-up, the patient was free from recurrences.
CONCLUSIONS: Recurrent hemorrhagic cysts should always be investigated and considered as a possible cancer lesion. Sonography and cytological exam are the first steps in case of suspicious cysts, but false-negative results are common. In such cases, resection of the cyst should be considered. Immediate resection is valid in cases of diagnostic uncertainty or inability to assess the cyst with imaging or biopsy.

Keywords: Breast Cyst, Triple Negative Breast Neoplasms

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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