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Sudden Esophageal Necrosis and Mediastinitis Associated with Invasive Candidiasis: A Case Report

Maria J. Riascos, Fredy A. Watts-Pajaro, Francisco L. Uribe-Buritica, José J. Serna, Oscar Rojas, Virginia Zarama Cordoba

(Department of Emergency Medicine, Universidad ICESI (ICESI University), Cali, Colombia)

Am J Case Rep 2021; 22:e928394

DOI: 10.12659/AJCR.928394


BACKGROUND: Esophageal necrosis is a rare entity characterized by the presence of extensive circumferential necrosis of the esophagus. It generally affects older adults who have associated chronic pathologies and has a reported mortality rate of approximately 32%. Most patients with esophageal necrosis have a complex clinical course.
CASE REPORT: We present the case of a 37-year-old man with idiopathic chronic renal failure who presented to the Emergency Department with sudden esophageal necrosis and mediastinitis, associated with invasive candidiasis. Diagnosis was challenging owing to the rarity of the condition. The patient required intensive care management and multiple surgical procedures.
CONCLUSIONS: Esophageal necrosis is an uncommon pathology that can be fatal because of associated complications. Its pathophysiology is unclear, and its treatment is based on the control of local injury and signs and symptoms. Acute esophageal necrosis associated with invasive Candida sp. infection is even more infrequent, with only a few cases reported in the literature.

Keywords: Candida albicans, Emergency Service, Hospital, Esophageal Diseases, Necrosis

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
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