Challenging differential diagnosis

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
204 32 0

30 Jul 2026 : Case report
Management of Shamblin Type III Carotid Body Tumor With Preoperative Embolization, Surgical Resection, and Rescue Endovascular Stroke Treatment: A Case Report
Michal S. Proczka
, Piotr Kaszczewski
, Michał M. Sajdek, Amelia Maciąg, Rafał Maciąg, Ireneusz Nawrot
, Zbigniew Gałązka
DOI: 10.12659/AJCR.951348
Am J Case Rep 2026; 27:e951348
204 32 0

28 Jul 2026 : Case report
Acute Small Bowel Obstruction as the First Manifestation of Occult Lung Adenocarcinoma: A Case Report of Jejunal Metastasis
Midani Touati, Ibtissem Korbi, Hiba Ben Hassine, Faiez Boughanmi
, Manel Njima, Sofiene Gaied Chortane, Faouzi Noomen
DOI: 10.12659/AJCR.953993
Am J Case Rep 2026; 27:e953993
287 31 0

28 Jul 2026 : Case report
Acute Small Bowel Obstruction as the First Manifestation of Occult Lung Adenocarcinoma: A Case Report of Jejunal Metastasis
Midani Touati, Ibtissem Korbi, Hiba Ben Hassine, Faiez Boughanmi
, Manel Njima, Sofiene Gaied Chortane, Faouzi Noomen
DOI: 10.12659/AJCR.953993
Am J Case Rep 2026; 27:e953993
287 31 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
308 237 0

21 Jul 2026 : Case report
Tuberculosis in the Context of Idiopathic CD4 Lymphocytopenia: A Case Report and Literature Review
Sara M. Alwarthan
, Abir Hamad Alsaid, Ashraf Ezzat Abdelsamad Attia
, Ahmed Alsahlawi
, Shahad Ali AlZahrani
, Khalid Ghazai Alotaibi
, Hassan Naasr Al Dhneem
, Marwan Jabr Alwazzeh
DOI: 10.12659/AJCR.953101
Am J Case Rep 2026; 27:e953101
308 237 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
224 233 0

17 Jul 2026 : Case report
Acquired Hemophilia A Revealing Occult Splenic Marginal Zone Lymphoma
Haripriya Susmitha Brahmanapalle, Alka Arora
DOI: 10.12659/AJCR.953683
Am J Case Rep 2026; 27:e953683
224 233 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
308 231 0

16 Jul 2026 : Case report
Heyde Syndrome Complicated by Pulmonary Embolism Before Transcatheter Aortic Valve Replacement: A Clinical Dilemma Between Bleeding and Thrombosis
Mingying Cao, Lingli Zhang, Ying Ren, Gejun Zhang
DOI: 10.12659/AJCR.953608
Am J Case Rep 2026; 27:e953608
308 231 0

10 Jul 2026 : Case report
Thoracolaparoscopic Esophagectomy for Severe Post-Corrosive Esophageal Stricture in a Young Adult: Implications for Minimally Invasive Surgical Practice
Kuanysh Kanatov
, Adil Shokebaev
, Bolatbek Baimakhanov
, Shakir Zhurayev
, Gulziya Ismailova
, Nurmakhan Imammyrzayev
, Nurbol Orynbassar
, Nazar Tolkyn
, Khozybek Kazakhstan
, Utkalbayev Garifulla
DOI: 10.12659/AJCR.953371
Am J Case Rep 2026; 27:e953371
290 281 0

10 Jul 2026 : Case report
Thoracolaparoscopic Esophagectomy for Severe Post-Corrosive Esophageal Stricture in a Young Adult: Implications for Minimally Invasive Surgical Practice
Kuanysh Kanatov
, Adil Shokebaev
, Bolatbek Baimakhanov
, Shakir Zhurayev
, Gulziya Ismailova
, Nurmakhan Imammyrzayev
, Nurbol Orynbassar
, Nazar Tolkyn
, Khozybek Kazakhstan
, Utkalbayev Garifulla
DOI: 10.12659/AJCR.953371
Am J Case Rep 2026; 27:e953371
290 281 0

09 Jul 2026 : Case report
Anterior ST-Segment Elevation Myocardial Infarction Shortly After Cefaclor Exposure: A Case Report Highlighting Kounis Syndrome as a Differential Diagnosis
Quan Zuo, Yue Zhu, Zhiwei Wang, Tao Ge
DOI: 10.12659/AJCR.953705
Am J Case Rep 2026; 27:e953705
359 310 0

09 Jul 2026 : Case report
Anterior ST-Segment Elevation Myocardial Infarction Shortly After Cefaclor Exposure: A Case Report Highlighting Kounis Syndrome as a Differential Diagnosis
Quan Zuo, Yue Zhu, Zhiwei Wang, Tao Ge
DOI: 10.12659/AJCR.953705
Am J Case Rep 2026; 27:e953705
359 310 0

08 Jul 2026 : Case report
A 31-Year-Old Woman With Liver Cirrhosis Due to Wilson Disease and the Double Impact of Active Tuberculosis and Anti-Tuberculosis Therapy Resulting in Acute Liver Injury
Petar Trifonov, Sonya Stefkova Dragneva, Donika K. Todovichin, Ivana Tihomirova Kitaeva, Rosen K. Nikolov
DOI: 10.12659/AJCR.953050
Am J Case Rep 2026; 27:e953050
412 367 0

08 Jul 2026 : Case report
A 31-Year-Old Woman With Liver Cirrhosis Due to Wilson Disease and the Double Impact of Active Tuberculosis and Anti-Tuberculosis Therapy Resulting in Acute Liver Injury
Petar Trifonov, Sonya Stefkova Dragneva, Donika K. Todovichin, Ivana Tihomirova Kitaeva, Rosen K. Nikolov
DOI: 10.12659/AJCR.953050
Am J Case Rep 2026; 27:e953050
412 367 0

22 Jun 2026 : Case report
Suspected Adult-Onset Congenital Myasthenic Syndrome Associated With a Heterozygous CHRND Variant in a Patient With Seropositive Rheumatoid Arthritis: A Case Report
Khaled Abdulwahab Amer
, Hanan Hassan Almalki
, Faisal Saud Alhudaithi
DOI: 10.12659/AJCR.952887
Am J Case Rep 2026; 27:e952887
463 547 0

22 Jun 2026 : Case report
Suspected Adult-Onset Congenital Myasthenic Syndrome Associated With a Heterozygous CHRND Variant in a Patient With Seropositive Rheumatoid Arthritis: A Case Report
Khaled Abdulwahab Amer
, Hanan Hassan Almalki
, Faisal Saud Alhudaithi
DOI: 10.12659/AJCR.952887
Am J Case Rep 2026; 27:e952887
463 547 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
171 195 0

03 Aug 2026 : Case report
Pustules in Stevens-Johnson Syndrome
Shunya Nagata, Takaie Kuki, Miyuki Kato
DOI: 10.12659/AJCR.953161
Am J Case Rep 2026; 27:e953161
171 195 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
239 173 0

02 Aug 2026 : Case report
Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis Presenting as Pyrexia of Unknown Origin With Splenic Masses
Nidhi Gupta, Kriti Yadav, Mythri Chittilla, Charly Almonte, Rahul Sampath
DOI: 10.12659/AJCR.952791
Am J Case Rep 2026; 27:e952791
239 173 0

17 Jun 2026 : Case report
Chlamydia trachomatis Pneumonia in a 50-Day-Old Full-Term Male Infant Associated With Mucus Plugging of the Left Upper Lobe Bronchus and Left Upper Lobe Atelectasis
Yuan Huang
, Meixia Huang, Liqin Ke, Shuxian Li, Xiaofen Tao, Guohong Zhu
DOI: 10.12659/AJCR.953643
Am J Case Rep 2026; 27:e953643
440 654 0

17 Jun 2026 : Case report
Chlamydia trachomatis Pneumonia in a 50-Day-Old Full-Term Male Infant Associated With Mucus Plugging of the Left Upper Lobe Bronchus and Left Upper Lobe Atelectasis
Yuan Huang
, Meixia Huang, Liqin Ke, Shuxian Li, Xiaofen Tao, Guohong Zhu
DOI: 10.12659/AJCR.953643
Am J Case Rep 2026; 27:e953643
440 654 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
219 169 0

01 Aug 2026 : Case report
Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series
Xiao-Yan Zhang
, Qiu-Li Zhang, Ying Liu, Li-Jie Zhu, Ying-Zhi Li, Xi-Ying Ye, Zhong-Jun Zhang, Yao-Xian Zhang
DOI: 10.12659/AJCR.953129
Am J Case Rep 2026; 27:e953129
219 169 0

29 Jul 2026 : Case report
Coronary Artery Embolism From Atrial Flutter Presenting as Cardiac Arrest and ST-Elevation Myocardial Infarction: Diagnostic and Therapeutic Challenges
Keyshla Pagán Morales, Keyur Patel
, Ammar Ahmed, Marcel Zughaib
DOI: 10.12659/AJCR.952062
Am J Case Rep 2026; 27:e952062
315 206 0

29 Jul 2026 : Case report
Coronary Artery Embolism From Atrial Flutter Presenting as Cardiac Arrest and ST-Elevation Myocardial Infarction: Diagnostic and Therapeutic Challenges
Keyshla Pagán Morales, Keyur Patel
, Ammar Ahmed, Marcel Zughaib
DOI: 10.12659/AJCR.952062
Am J Case Rep 2026; 27:e952062
315 206 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
271 234 0

30 Jul 2026 : Case report
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Nanami Ichihashi, Motona Kumagai
, Miyako Shimasaki, Akihiro Shioya
, Sohsuke Yamada
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
271 234 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
269 189 0

27 Jul 2026 : Case report
Transient Cardiac Dysfunction Due to New-Onset Mitral Chordal Rupture With Concomitant Congenital Absence of the Right Coronary Artery: A Case Report
Songyan Zhang, Ying Cui, Shucheng Li
DOI: 10.12659/AJCR.952798
Am J Case Rep 2026; 27:e952798
269 189 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
394 329 0

25 Jul 2026 : Case report
A 46-Year-Old Man Presenting With Chest Pain Due to Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Diagnosed by Multimodal Cardiac Imaging
Mauro de Deus Passos, Daniel Lopes Marques de Araújo, Lucas de Ávila Mariano, Dilson Palhares Ferreira, Luciano Moreira Alves, Simone Nascimento dos Santos
DOI: 10.12659/AJCR.953259
Am J Case Rep 2026; 27:e953259
394 329 0

24 Jul 2026 : Case report
Adult-Onset Central Nervous System Embryonal Tumor With Neuronal Differentiation: A Diagnostic Challenge
Anh Quynh Pham, Tuyen Van Pham, Thong Minh Pham
DOI: 10.12659/AJCR.953049
Am J Case Rep 2026; 27:e953049
296 277 0

24 Jul 2026 : Case report
Adult-Onset Central Nervous System Embryonal Tumor With Neuronal Differentiation: A Diagnostic Challenge
Anh Quynh Pham, Tuyen Van Pham, Thong Minh Pham
DOI: 10.12659/AJCR.953049
Am J Case Rep 2026; 27:e953049
296 277 0

22 Jul 2026 : Case report
Diagnostic Challenges and Scientific Management of Suspected Recurrent Kikuchi-Fujimoto Disease: A Case Report
DOI: 10.12659/AJCR.952658
Am J Case Rep 2026; 27:e952658
309 323 0

22 Jul 2026 : Case report
Diagnostic Challenges and Scientific Management of Suspected Recurrent Kikuchi-Fujimoto Disease: A Case Report
DOI: 10.12659/AJCR.952658
Am J Case Rep 2026; 27:e952658
309 323 0

16 Jul 2026 : Case report
Machine Perfusion as a Temporal and Resuscitative Bridge in Emergent Renal Autotransplantation: A Novel Case Report
Mariah Johnson
, William Archie, Namratha Mylarapu, Dionisios Vrochides, Maria Baimas-George, Vincent Casingal
DOI: 10.12659/AJCR.953068
Am J Case Rep 2026; 27:e953068
298 281 0

16 Jul 2026 : Case report
Machine Perfusion as a Temporal and Resuscitative Bridge in Emergent Renal Autotransplantation: A Novel Case Report
Mariah Johnson
, William Archie, Namratha Mylarapu, Dionisios Vrochides, Maria Baimas-George, Vincent Casingal
DOI: 10.12659/AJCR.953068
Am J Case Rep 2026; 27:e953068
298 281 0

20 Jul 2026 : Case report
Case Report: Primary Central Nervous System Lymphoma With “Wine Glass” Sign Presenting as Somnolence and Fatigue
RuPing Xu, XingYong Chen
DOI: 10.12659/AJCR.952923
Am J Case Rep 2026; 27:e952923
352 296 0

20 Jul 2026 : Case report
Case Report: Primary Central Nervous System Lymphoma With “Wine Glass” Sign Presenting as Somnolence and Fatigue
RuPing Xu, XingYong Chen
DOI: 10.12659/AJCR.952923
Am J Case Rep 2026; 27:e952923
352 296 0

18 Jul 2026 : Case report
A 79-Year-Old Woman With Stage IIIB Lung Squamous Cell Carcinoma Presenting With Late-Onset Durvalumab‑Associated Myocarditis Requiring Differentiation From Pericardial Invasion
Norio Kodaka, Fumiyuki Hayashi, Yuki Yokouchi, Masahiro Yoshida, Hiroto Matsuse
DOI: 10.12659/AJCR.953001
Am J Case Rep 2026; 27:e953001
396 322 0

18 Jul 2026 : Case report
A 79-Year-Old Woman With Stage IIIB Lung Squamous Cell Carcinoma Presenting With Late-Onset Durvalumab‑Associated Myocarditis Requiring Differentiation From Pericardial Invasion
Norio Kodaka, Fumiyuki Hayashi, Yuki Yokouchi, Masahiro Yoshida, Hiroto Matsuse
DOI: 10.12659/AJCR.953001
Am J Case Rep 2026; 27:e953001
396 322 0

17 Jul 2026 : Case report
Two Cases of Malaria-Associated Acute Respiratory Distress Syndrome and Severe Pulmonary Complications From Plasmodium falciparum in Tanzania
Hilary Chipongo, Samina Chaki
, Esmail Sangey
, Ronald Mclarty, Rawya S.A. Baabde, Kaushik Ramaiya
DOI: 10.12659/AJCR.951737
Am J Case Rep 2026; 27:e951737
439 402 0

17 Jul 2026 : Case report
Two Cases of Malaria-Associated Acute Respiratory Distress Syndrome and Severe Pulmonary Complications From Plasmodium falciparum in Tanzania
Hilary Chipongo, Samina Chaki
, Esmail Sangey
, Ronald Mclarty, Rawya S.A. Baabde, Kaushik Ramaiya
DOI: 10.12659/AJCR.951737
Am J Case Rep 2026; 27:e951737
439 402 0

15 Jul 2026 : Case report
Ultrasound Identification of Right Internal Jugular Vein Occlusion After Catheterization in a Premature Infant
Haikou Yang, Qianhui Xu, Jun Wang
DOI: 10.12659/AJCR.952818
Am J Case Rep 2026; 27:e952818
307 303 0

15 Jul 2026 : Case report
Ultrasound Identification of Right Internal Jugular Vein Occlusion After Catheterization in a Premature Infant
Haikou Yang, Qianhui Xu, Jun Wang
DOI: 10.12659/AJCR.952818
Am J Case Rep 2026; 27:e952818
307 303 0

14 Jul 2026 : Case report
Primary Small Cell Neuroendocrine Carcinoma of the Breast in a 75-Year-Old Woman With Aggressive Recurrence Despite Multimodal Therapy: A Case Report and Literature Review
Shefa Abdullah Alamoudi
, Hadeel Elwaheidi, Hanan Albishi, Sarah Aldosari
, Asma M. Tulbah, Wafa Alkhayal
DOI: 10.12659/AJCR.952443
Am J Case Rep 2026; 27:e952443
326 305 0

14 Jul 2026 : Case report
Primary Small Cell Neuroendocrine Carcinoma of the Breast in a 75-Year-Old Woman With Aggressive Recurrence Despite Multimodal Therapy: A Case Report and Literature Review
Shefa Abdullah Alamoudi
, Hadeel Elwaheidi, Hanan Albishi, Sarah Aldosari
, Asma M. Tulbah, Wafa Alkhayal
DOI: 10.12659/AJCR.952443
Am J Case Rep 2026; 27:e952443
326 305 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952909
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950868
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952931
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952577
Most Viewed Current Articles
07 Dec 2021 : Case report
22,759,844
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report
176,022
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
120,540
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
65,552
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
